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The most commonly used probiotics are bacteria of genera Lactobacillus or Bifidobacterium. Their beneficial effects are based on: promotion of resistance to enteric pathogens, prevention of small bowel bacterial overgrowth and immune system modulation. Probiotics are defined as live microorganisms which confer a beneficial health effect on a human host. Lactobacillus reuteri in treatment of functional abdominal pain in children Condition or diseaseĭietary Supplement: Administration of L.reuteri in children with abdominal pain Dietary Supplement: Administration of placebo in children with abdominal pain Dietary Supplement: Administration of L.reuteri in children with constipation Dietary Supplement: Administration of placebo in children with constipation Frequency of defecation, stool consistency and need for lactulose will be recorded in children with chronic constipation. Frequency and intensity of episodes of abdominal pain during and after intervention will be recorded in children with FAP. reuteri in a daily dose of 108 CFU and lactulose, or placebo and lactulose. Children with chronic constipation will receive either L. reuteri in a daily dose of 108 CFU, or placebo during three months. Children with FAP will be randomized in one of two groups and will receive either L. Although there is evidence that probiotics increase stool frequency and decrease stool consistency in healthy individuals the evidence for efficacy in constipation is limited.Ĭhildren with functional abdominal pain (FAP) and constipation will be included in the study. Why Should I Register and Submit Results?īeneficial therapeutic effect of probiotics has been reported in children with irritable bowel syndrome, but not consistently in other functional gastrointestinal disorders.